Institut Pasteur warns influenza risks persist as global flu season accelerates

Institut Pasteur warns influenza risks persist as global flu season accelerates
Flu season ahead sign
Saturday 27 December 2025 - 12:03

Scientists at the Institut Pasteur in Paris have renewed warnings about the global risks posed by influenza viruses, as an unusually early and fast moving flu season takes shape across parts of the northern hemisphere, including Europe, North Africa and the eastern Mediterranean.

Researchers at the Institut Pasteur have stressed that while the overall public health risk remains low, influenza continues to pose structural pandemic risks because population immunity is uneven and seasonal dynamics can shift rapidly. 

The warning comes as surveillance data show influenza activity rising earlier than usual in several regions.

According to the World Health Organization, influenza A viruses are dominating current detections, with the H3N2 subtype prevailing.

 Covid 19 continues to circulate at low background levels, while respiratory syncytial virus activity is beginning to increase. Health agencies note that early timing can accelerate transmission before public health systems and seasonal behavior fully adjust.

Seasonal influenza viruses are familiar, but not benign. Historically, H3N2 dominant seasons have been associated with higher hospitalization rates among older adults and increased strain on healthcare systems. 

Seasonal flu vaccines are reformulated months in advance based on global projections, and partial mismatches between vaccine composition and circulating strains are common.

 While vaccines continue to reduce severe illness and deaths, protection against infection may be lower in some seasons.

The broader concern highlighted by international experts extends beyond seasonal flu.

Global health agencies, including WHO, the Food and Agriculture Organization and the World Organisation for Animal Health, continue to monitor avian influenza viruses, including highly pathogenic H5 strains. 

These viruses remain primarily animal borne, with human infections rare and linked mainly to close contact with infected animals. 

Joint assessments currently classify the risk to the general public as low, while emphasizing the need for vigilance and surveillance due to the lack of population immunity to H5 viruses.

Recent outbreaks of avian influenza among mammals have reinforced monitoring efforts, as expanded host range increases opportunities for viral adaptation, even though no sustained human to human transmission has been observed.

Within this international context, several countries are reporting early seasonal flu activity. 

In Morocco, clinicians have reported increased influenza like illness since mid November, earlier than the typical winter peak. Health authorities there continue routine monitoring, and there is no indication of unusual viral strains or links to avian influenza.

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